Introduction to Genetics

고려대학교
이진협

페이스북 트위터 카카오톡 네이버밴드 링크복사

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자연과학 >생활과학 >식품공학
강의학기

2015년 2학기

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강의계획서

KFBT212 Introduction to Genetics course will examine the central dogma of molecular biology which is the logical explanation of the flow of genetic information within a biological system, and thus discuss DNA, RNA, and protein, and how their synthesis, such as DNA replication, transcription, RNA processing, and translation, is regulated as the fundamental architecture of the course.

차시별 강의

1.	Heredity, Genes, and DNA	nature, Heredity, Unity, Inheritance of genes, Inheritance of Chromosome, genetic material, Nucleic acid, protein
2.	Heredity, Genes, and DNA	griffith experiment, transformation of bacteria, chargaff's rule, Molecular structure of DNA
3.	Expression of Genetic Information	Central Dogma, Replication of DNA, Role of messenger RNA, Discovery of introns, Role of introns, Determination of genetic code, Discovery of transfer RNA
4.	Replication & Maintenance	The flow of genetic information, DNA Replication, DNA Polymerase, Fidelity of DNA replication, Fidelity of DNA polymerase
5.	Replication & Maintenance	Semi-continuous DNA replication, Synthesis of leading & lagging strands of DNA, Continuous synthesis of lagging strands of DNA, Different polymerases in procaryotic and eukaryotic cells
6.	Topoisomerase during DNA replication	Coordinated DNA synthesis, Origin of replication, Priming of replication, Telomere & Telomerase: Maintaining the end of DNA, Termination of replication
7.	RNA Synthesis and Processing	RNA Synthesis and Processing, Structure of RNA polymerase, Status of RNA polymerase, Binding of RNA polymerase
8.	Characteristics of promoter	Characteristics of promoter, Initiation of transcription, Elongation of transcription, Termination of transcription, Dissociation of RNA polymerase, Same initiation Different termination
9.	How the transcription is regulated?	Where the transcription is regulated?, How transcription is regulated in the stage of initiation?, How transcription is regulated in the stage of initiation?, transcriptional regulation of lac operon, Regulation of transcription in eukaryotes
10.	Protein Synthesis	decoding, Direction of translation, Transfer RNA, Wobble base pairing, Status of ribosome complex, Initiation of translation, Elongation of translation, Termination of translation , Polysomes of translation
11.	DNA Repair and Recombination	DNA damage DNA repair
12.	DNA Damage can be detected and repaired	DNA Repair, DNA Integrity, Exonuclease, Endonuclease, Excision, Incision, Recombination Repair